Pharmacodynamics for Drug Discovery

Pharmacodynamics for Drug Discovery - Package of all 3 Modules

Module 1: Basic Pharmacological Principles, Agonism and the Operational Model
(February 17, 2010 at 11:30 AM EST, 10:30 AM CST, 9:30 AM MST, 8:30 AM PST)

Module 2: Orthosteric and Allosteric Antagonism: Methods of Measurement
(February 24, 2010 at 11:30 AM EST, 10:30 AM CST, 9:30 AM MST, 8:30 AM PST)

Module 3: Structure of Drug Discovery Programs: Target Selection, Assay Development and Criteria for Activity
(March 3, 2010 at 11:30 AM EST, 10:30 AM CST, 9:30 AM MST, 8:30 AM PST)

Human Primary Cells & Stem Cells in Drug Discovery Application

Human Primary Cells & Stem Cells in Drug Discovery Application - Package of all 4

Module 1: Primary Cells in Compound Screening: From Neurons to Novel Drug Candidate
(October 7, 2009)
 

Module 2: Preparation and Maintenance of Stem Cells and Primary Cells for Drug Discovery Initiatives
(October 14, 2009)
 

Module 3: Library Screening and Potential Therapeutic Applications of Stem Cell Preparations
(October 21, 2009)
 

Module 4: Reverse Engineering: Selected Techniques to Establish and Validate Targets Found by Phenotype Screening
(October 28, 2009)
 

Fundamentals of ADME and Toxicology Assessment for Pre-Clinical Drug Discovery

Fundamentals of ADME and Toxicology Assessment for Pre-Clinical Drug Discovery - Package of all 4 Modules

Module 1: Introduction to the Principles of In Vitro ADME
(September 8, 2009)
 

Module 2: Drug Metabolism and Drug-Drug Interactions
(September 15, 2009)
 

Module 3: Safety/Toxicology Integrated Risk Assessment
(September 22, 2009)
 

Module 4: Major Elements of Organ-Toxicity
(September 29, 2009)
 

Enzymology for Drug Discovery

Enzymology for Drug Discovery - Package of all 4 Modules

Module 1: Enzymes as Drug Targets and Actions of Inhibitors
(March 18, 2009)
 

Module 2: Measurement of Enzyme: Inhibitor Interactions
(March 25, 2009)
 

Module 3: Practical Kinetics for Elucidating Enzyme Mechanisms in Drug Discovery Part 1
(April 1, 2009)
 

Module 4: Practical Kinetics for Elucidating Enzyme Mechanisms in Drug Discovery Part 2
(April 8, 2009)
 

Label-Free Technologies for Drug Discovery and Physiology

Label-Free Technologies for Drug Discovery and Physiology - Package of all 3 Modules

Module 1: The Power of Mass Spectrometry as a Label-Free Detection Platform
(November 4, 2008)
 

Module 2: Label Free Techniques To Assess Ligand Binding
(November 11, 2008)
 

Module 3: Cell-Based Assays Utilizing Label-Free Technologies
(November 18, 2008)
 

Cell-Based Assays for Drug Discovery Virtual Course

Cell-Based Assays for Drug Discovery Virtual Course - Package of All 5 Modules

Module 1: Cells: Things to Remember
(September 30, 2008)
 

Module 2: Cells as Reagents
(October 7, 2008)
 

Module 3: Developing Cell-Based Assays for GPCRs and Ion Channels
(October 14, 2008)
 

Module 4: Cell-Based Assays for Pathway Analysis
(October 21, 2008)
 

Module 5: Cell-Based Assays for Target Validation
(October 28, 2008)
 

Medicinal Chemistry Concepts for Biologists

Medicinal Chemistry Concepts for Biologists - Package of All 4 Modules

Medicinal Chemistry Concepts Mod 1: Introduction to Medicinal Chemistry: It’s all about the Molecules
(March 5, 2008)
 

Medicinal Chemistry Concepts Mod 2: Lead compounds:The Good, the Bad and the Ugly
(March 12, 2008)
 

Medicinal Chemistry Concepts Mod 3: Compound Optimization, Part 1: You Mean it’s More than Potency
(March 19, 2008)
 

Medicinal Chemistry Concepts Mod 4: Compound optimization, Part 2: Are We There Yet?
(March 26, 2008)
 

HTS Basics:Theory and Practice of High-Throughput Screening against Chemical Libraries

HTS Basics: Theory and Practice of High-Throughput Screening against Chemical Libraries - Package of all 5

HTS Basics Module 1: Overview of Strategies and Methods in HTS
(October 3, 2007)
 

HTS Basics Module 2: Liquid Handling and Detection Technologies in HTS
(October 10, 2007)
 

HTS Basics Module 3: Statistical Considerations in the Optimization and Validation of HTS assays
(October 17, 2007)
 

HTS Basics Module 4: Issues in Storage and Management of Compound Collections
(October 24, 2007)
 

HTS Basics Module 5: HTS Case Studies and Lessons Learned
(October 30, 2007)
 

The Biomolecular Sciences of Protein Kinase-Targeted Compound Discovery Virtual Series

The Biomolecular Sciences of Protein Kinase-Targeted Compound Discovery: Package of All 4 Modules

Module 1: The Kinome: Small Molecule Discovery and Pharmacology
(April 27, 2006)
 

Module 2: Cell based and Biochemical Assay Strategies for Kinase Screening and Profiling
(May 4, 2006)
 

Module 3: Chemical Library Development and Lead Optimization of Kinase Inhibitors
(May 11, 2006)
 

Module 4: Development and Clinical Trials for Kinase Targeted Compounds
(May 24, 2006)